Population Pharmacokinetics and Pharmacodynamics of Lampalizumab Administered Intravitreally to Patients With Geographic Atrophy

Intravitreally administered lampalizumab is an investigational complement inhibitor directed against complement factor D (CFD) for the treatment of geographic atrophy (GA) secondary to age-related macular degeneration. We sought to develop an integrated ocular and systemic pharmacokinetic/pharmacody...

Descripción completa

Detalles Bibliográficos
Autores principales: Le, KN, Gibiansky, L, van Lookeren Campagne, M, Good, J, Davancaze, T, Loyet, KM, Morimoto, A, Strauss, EC, Jin, JY
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625864/
https://www.ncbi.nlm.nih.gov/pubmed/26535160
http://dx.doi.org/10.1002/psp4.12031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625864/
https://www.ncbi.nlm.nih.gov/pubmed/26535160
http://dx.doi.org/10.1002/psp4.12031

Ejemplares similares