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Population Pharmacokinetics and Pharmacodynamics of Lampalizumab Administered Intravitreally to Patients With Geographic Atrophy

Intravitreally administered lampalizumab is an investigational complement inhibitor directed against complement factor D (CFD) for the treatment of geographic atrophy (GA) secondary to age-related macular degeneration. We sought to develop an integrated ocular and systemic pharmacokinetic/pharmacody...

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Detalles Bibliográficos
Autores principales:	Le, KN, Gibiansky, L, van Lookeren Campagne, M, Good, J, Davancaze, T, Loyet, KM, Morimoto, A, Strauss, EC, Jin, JY
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625864/ https://www.ncbi.nlm.nih.gov/pubmed/26535160 http://dx.doi.org/10.1002/psp4.12031

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