Sildenafil reduces neuroinflammation and restores spatial learning in rats with hepatic encephalopathy: underlying mechanisms

BACKGROUND: There are no specific treatments for the neurological alterations of cirrhotic patients with minimal hepatic encephalopathy (MHE). Rats with MHE due to portacaval shunt (PCS) show impaired spatial learning. The underlying mechanisms remain unknown. The aims of this work were to assess: (...

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Detalles Bibliográficos
Autores principales: Hernandez-Rabaza, Vicente, Agusti, Ana, Cabrera-Pastor, Andrea, Fustero, Santos, Delgado, Oscar, Taoro-Gonzalez, Lucas, Montoliu, Carmina, Llansola, Marta, Felipo, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625867/
https://www.ncbi.nlm.nih.gov/pubmed/26511444
http://dx.doi.org/10.1186/s12974-015-0420-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625867/
https://www.ncbi.nlm.nih.gov/pubmed/26511444
http://dx.doi.org/10.1186/s12974-015-0420-7

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