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Antitumor activity of the multikinase inhibitor regorafenib in patient-derived xenograft models of gastric cancer
BACKGROUND: Unresectable gastric cancer is associated with poor outcomes, with few treatment options available after failure of cytotoxic chemotherapy. Clinical trials of targeted therapies have generally shown no survival benefit in gastric cancer, with the exceptions of the antibodies ramucirumab...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625870/ https://www.ncbi.nlm.nih.gov/pubmed/26514182 http://dx.doi.org/10.1186/s13046-015-0243-5 |