Characterizing selective pressures on the pathway for de novo biosynthesis of pyrimidines in yeast

BACKGROUND: Selection on proteins is typically measured with the assumption that each protein acts independently. However, selection more likely acts at higher levels of biological organization, requiring an integrative view of protein function. Here, we built a kinetic model for de novo pyrimidine...

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Detalles Bibliográficos
Autores principales: Hermansen, Russell A., Mannakee, Brian K., Knecht, Wolfgang, Liberles, David A., Gutenkunst, Ryan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625875/
https://www.ncbi.nlm.nih.gov/pubmed/26511837
http://dx.doi.org/10.1186/s12862-015-0515-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625875/
https://www.ncbi.nlm.nih.gov/pubmed/26511837
http://dx.doi.org/10.1186/s12862-015-0515-x

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