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Inflammatory response of endothelial cells to a human endogenous retrovirus associated with multiple sclerosis is mediated by TLR4

The MSRV (multiple sclerosis-associated retrovirus) belongs to the human endogenous retrovirus HERV-W family. The envelope protein originating from the MSRV has been found in most patients with multiple sclerosis (MS). This protein (Env-ms) has pro-inflammatory properties for several types of immune...

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Detalles Bibliográficos
Autores principales: Duperray, Alain, Barbe, Delphin, Raguenez, Gilda, Weksler, Babette B., Romero, Ignacio A., Couraud, Pierre-Olivier, Perron, Hervé, Marche, Patrice N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625887/
https://www.ncbi.nlm.nih.gov/pubmed/25957268
http://dx.doi.org/10.1093/intimm/dxv025