Robust and efficient parameter estimation in dynamic models of biological systems

BACKGROUND: Dynamic modelling provides a systematic framework to understand function in biological systems. Parameter estimation in nonlinear dynamic models remains a very challenging inverse problem due to its nonconvexity and ill-conditioning. Associated issues like overfitting and local solutions...

Descripción completa

Detalles Bibliográficos
Autores principales: Gábor, Attila, Banga, Julio R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625902/
https://www.ncbi.nlm.nih.gov/pubmed/26515482
http://dx.doi.org/10.1186/s12918-015-0219-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625902/
https://www.ncbi.nlm.nih.gov/pubmed/26515482
http://dx.doi.org/10.1186/s12918-015-0219-2

Ejemplares similares