Changes in correlation between promoter methylation and gene expression in cancer

BACKGROUND: Methylation of high-density CpG regions known as CpG Islands (CGIs) has been widely described as a mechanism associated with gene expression regulation. Aberrant promoter methylation is considered a hallmark of cancer involved in silencing of tumor suppressor genes and activation of onco...

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Detalles Bibliográficos
Autores principales: Moarii, Matahi, Boeva, Valentina, Vert, Jean-Philippe, Reyal, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625954/
https://www.ncbi.nlm.nih.gov/pubmed/26510534
http://dx.doi.org/10.1186/s12864-015-1994-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625954/
https://www.ncbi.nlm.nih.gov/pubmed/26510534
http://dx.doi.org/10.1186/s12864-015-1994-2

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