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Local but Not Systemic Administration of Uridine Prevents Development of Antigen-Induced Arthritis

OBJECTIVE: Uridine has earlier been show to down modulate inflammation in models of lung inflammation. The aim of this study was to evaluate the anti-inflammatory effect of uridine in arthritis. METHODS: Arthritis was induced by intra-articular injection of mBSA in the knee of NMRI mice pre-immunize...

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Detalles Bibliográficos
Autores principales: Chenna Narendra, Sudeep, Chalise, Jaya Prakash, Magnusson, Mattias, Uppugunduri, Srinivas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625961/
https://www.ncbi.nlm.nih.gov/pubmed/26512984
http://dx.doi.org/10.1371/journal.pone.0141863