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Dimethylsulfoxide excerbates cisplatin-induced cytotoxicity in Ehrlich ascites carcinoma cells

BACKGROUND: Cisplatin (CIS) is a potent antineoplastic agent with high therapeutic efficacy against many kinds of tumors. Its use is limited by its nephrotoxicity. The aim of this work was to minimize cisplatin effective dose and the possible reduction of its severe side effects. The present study w...

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Detalles Bibliográficos
Autores principales: Osman, Abdel-Moneim M., Alqahtani, Ali A., Damanhouri, Zoheir A., Al-Harthy, Sameer E., ElShal, Mohamed F., Ramadan, Wafaa S., Kamel, Fatemah, Osman, Mohamed A. M., Khan, Lateef M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625967/
https://www.ncbi.nlm.nih.gov/pubmed/26516314
http://dx.doi.org/10.1186/s12935-015-0258-1