The Role of Structural Elements of the 5'-Terminal Region of p53 mRNA in Translation under Stress Conditions Assayed by the Antisense Oligonucleotide Approach

The p53 protein is one of the major factors responsible for cell cycle regulation and stress response. In the 5’-terminal region of p53 mRNA, an IRES element has been found which takes part in the translational regulation of p53 expression. Two characteristic hairpin motifs are present in this mRNA...

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Detalles Bibliográficos
Autores principales: Swiatkowska, Agata, Zydowicz, Paulina, Gorska, Agnieszka, Suchacka, Julia, Dutkiewicz, Mariola, Ciesiołka, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626026/
https://www.ncbi.nlm.nih.gov/pubmed/26513723
http://dx.doi.org/10.1371/journal.pone.0141676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626026/
https://www.ncbi.nlm.nih.gov/pubmed/26513723
http://dx.doi.org/10.1371/journal.pone.0141676

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