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Solution Structural Studies of GTP:Adenosylcobinamide-Phosphateguanylyl Transferase (CobY) from Methanocaldococcus jannaschii

GTP:adenosylcobinamide-phosphate (AdoCbi-P) guanylyl transferase (CobY) is an enzyme that transfers the GMP moiety of GTP to AdoCbi yielding AdoCbi-GDP in the late steps of the assembly of Ado-cobamides in archaea. The failure of repeated attempts to crystallize ligand-free (apo) CobY prompted us to...

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Detalles Bibliográficos
Autores principales: Singarapu, Kiran K., Otte, Michele M., Tonelli, Marco, Westler, William M., Escalante-Semerena, Jorge C., Markley, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626045/
https://www.ncbi.nlm.nih.gov/pubmed/26513744
http://dx.doi.org/10.1371/journal.pone.0141297