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Phosphorylation of the Scc2 cohesin deposition complex subunit regulates chromosome condensation through cohesin integrity

The cohesion of replicated sister chromatids promotes chromosome biorientation, gene regulation, DNA repair, and chromosome condensation. Cohesion is mediated by cohesin, which is deposited on chromosomes by a separate conserved loading complex composed of Scc2 and Scc4 in Saccharomyces cerevisiae....

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Detalles Bibliográficos
Autores principales: Woodman, Julie, Hoffman, Matthew, Dzieciatkowska, Monika, Hansen, Kirk C., Megee, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626061/
https://www.ncbi.nlm.nih.gov/pubmed/26354421
http://dx.doi.org/10.1091/mbc.E15-03-0165