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Phosphorylation of the Scc2 cohesin deposition complex subunit regulates chromosome condensation through cohesin integrity
The cohesion of replicated sister chromatids promotes chromosome biorientation, gene regulation, DNA repair, and chromosome condensation. Cohesion is mediated by cohesin, which is deposited on chromosomes by a separate conserved loading complex composed of Scc2 and Scc4 in Saccharomyces cerevisiae....
Autores principales: | Woodman, Julie, Hoffman, Matthew, Dzieciatkowska, Monika, Hansen, Kirk C., Megee, Paul C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626061/ https://www.ncbi.nlm.nih.gov/pubmed/26354421 http://dx.doi.org/10.1091/mbc.E15-03-0165 |
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