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MDM1 is a microtubule-binding protein that negatively regulates centriole duplication

Mouse double-minute 1 (Mdm1) was originally identified as a gene amplified in transformed mouse cells and more recently as being highly up-regulated during differentiation of multiciliated epithelial cells, a specialized cell type having hundreds of centrioles and motile cilia. Here we show that the...

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Detalles Bibliográficos
Autores principales: Van de Mark, Daniel, Kong, Dong, Loncarek, Jadranka, Stearns, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626064/
https://www.ncbi.nlm.nih.gov/pubmed/26337392
http://dx.doi.org/10.1091/mbc.E15-04-0235