p38 MAP kinase–dependent phosphorylation of the Gp78 E3 ubiquitin ligase controls ER–mitochondria association and mitochondria motility

Gp78 is an ERAD-associated E3 ubiquitin ligase that induces degradation of the mitofusin mitochondrial fusion proteins and mitochondrial fission. Gp78 is localized throughout the ER; however, the anti-Gp78 3F3A monoclonal antibody (mAb) recognizes Gp78 selectively in mitochondria-associated ER domai...

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Detalles Bibliográficos
Autores principales: Li, Lei, Gao, Guang, Shankar, Jay, Joshi, Bharat, Foster, Leonard J., Nabi, Ivan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626067/
https://www.ncbi.nlm.nih.gov/pubmed/26337390
http://dx.doi.org/10.1091/mbc.E15-02-0120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626067/
https://www.ncbi.nlm.nih.gov/pubmed/26337390
http://dx.doi.org/10.1091/mbc.E15-02-0120

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