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Ccq1-Tpz1(TPP1) interaction facilitates telomerase and SHREC association with telomeres in fission yeast

Evolutionarily conserved shelterin complex is essential for telomere maintenance in the fission yeast Schizosaccharomyces pombe. Elimination of the fission yeast shelterin subunit Ccq1 causes progressive loss of telomeres due to the inability to recruit telomerase, activates the DNA damage checkpoin...

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Detalles Bibliográficos
Autores principales: Moser, Bettina A., Raguimova, Olga N., Nakamura, Toru M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626069/
https://www.ncbi.nlm.nih.gov/pubmed/26354422
http://dx.doi.org/10.1091/mbc.E15-07-0481