PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena

During breast cancer progression, alternative mRNA splicing produces functionally distinct isoforms of Mena, an actin regulator with roles in cell migration and metastasis. Aggressive tumor cell subpopulations express Mena(INV), which promotes tumor cell invasion by potentiating EGF responses. Howev...

Descripción completa

Detalles Bibliográficos
Autores principales: Hughes, Shannon K., Oudin, Madeleine J., Tadros, Jenny, Neil, Jason, Del Rosario, Amanda, Joughin, Brian A., Ritsma, Laila, Wyckoff, Jeff, Vasile, Eliza, Eddy, Robert, Philippar, Ulrike, Lussiez, Alisha, Condeelis, John S., van Rheenen, Jacco, White, Forest, Lauffenburger, Douglas A., Gertler, Frank B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626070/
https://www.ncbi.nlm.nih.gov/pubmed/26337385
http://dx.doi.org/10.1091/mbc.E15-06-0442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626070/
https://www.ncbi.nlm.nih.gov/pubmed/26337385
http://dx.doi.org/10.1091/mbc.E15-06-0442

Ejemplares similares