Cargando…

PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena

During breast cancer progression, alternative mRNA splicing produces functionally distinct isoforms of Mena, an actin regulator with roles in cell migration and metastasis. Aggressive tumor cell subpopulations express Mena(INV), which promotes tumor cell invasion by potentiating EGF responses. Howev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hughes, Shannon K., Oudin, Madeleine J., Tadros, Jenny, Neil, Jason, Del Rosario, Amanda, Joughin, Brian A., Ritsma, Laila, Wyckoff, Jeff, Vasile, Eliza, Eddy, Robert, Philippar, Ulrike, Lussiez, Alisha, Condeelis, John S., van Rheenen, Jacco, White, Forest, Lauffenburger, Douglas A., Gertler, Frank B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626070/ https://www.ncbi.nlm.nih.gov/pubmed/26337385 http://dx.doi.org/10.1091/mbc.E15-06-0442

Ejemplares similares

Mena(INV) mediates synergistic cross-talk between signaling pathways driving chemotaxis and haptotaxis
por: Oudin, Madeleine J., et al.
Publicado: (2016)

The alternatively-included 11a sequence modifies the effects of Mena on actin cytoskeletal organization and cell behavior
por: Balsamo, Michele, et al.
Publicado: (2016)

Mena(INV) dysregulates cortactin phosphorylation to promote invadopodium maturation
por: Weidmann, Maxwell D., et al.
Publicado: (2016)

Simultaneous imaging of GFP, CFP and collagen in tumors in vivo using multiphoton microscopy
por: Sahai, Erik, et al.
Publicado: (2005)

Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors
por: Roussos, Evanthia T, et al.
Publicado: (2010)

Quantitative assessment of invasive mena isoforms (Mena(calc)) as an independent prognostic marker in breast cancer
por: Agarwal, Seema, et al.
Publicado: (2012)

Mena binds α5 integrin directly and modulates α5β1 function
por: Gupton, Stephanie L., et al.
Publicado: (2012)

Imaging windows for long-term intravital imaging: General overview and technical insights
por: Alieva, Maria, et al.
Publicado: (2014)

Brief Report: Intravital Imaging of Cancer Stem Cell Plasticity in Mammary Tumors
por: Zomer, Anoek, et al.
Publicado: (2013)

Mena(calc), a quantitative method of metastasis assessment, as a prognostic marker for axillary node-negative breast cancer
por: Forse, Catherine L., et al.
Publicado: (2015)

Mena–GRASP65 interaction couples actin polymerization to Golgi ribbon linking
por: Tang, Danming, et al.
Publicado: (2016)

Capping Protein Terminates but Does Not Initiate Chemoattractant-induced Actin Assembly in Dictyostelium
por: Eddy, R.J., et al.
Publicado: (1997)

Endophilin, Lamellipodin, and Mena cooperate to regulate F-actin-dependent EGF-receptor endocytosis
por: Vehlow, Anne, et al.
Publicado: (2013)

Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/Mena(INV)-initiated invadopodium formation
por: Pignatelli, Jeanine, et al.
Publicado: (2016)

Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition
por: Stopfer, Lauren E., et al.
Publicado: (2020)

Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodeling
por: Hoffman, Laura M., et al.
Publicado: (2006)

Dendra2 Photoswitching through the Mammary Imaging Window
por: Gligorijevic, Bojana, et al.
Publicado: (2009)

Intestinal crypt homeostasis revealed at single stem cell level by in vivo live-imaging
por: Ritsma, Laila, et al.
Publicado: (2014)

hMENA(11a), a hMENA isoform sending survival signals
por: Trono, Paola, et al.
Publicado: (2015)

Cooperative NF-κB and Notch1 signaling promotes macrophage-mediated MenaINV expression in breast cancer
por: Duran, Camille L., et al.
Publicado: (2023)

COVID-19 in the MENA region
por: Abbara, Aula
Publicado: (2023)

Pedro de Mena : escultor, 1628-1688 /
por: Gila Medina, Lázaro
Publicado: (2007)

5′-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion
por: Rajadurai, Charles V., et al.
Publicado: (2016)

Juan de Mena : poeta del prerrenacimiento español
por: Lida de Malkiel, María Rosa
Publicado: (1984)

The actin modulator hMENA regulates GAS6‐AXL axis and pro‐tumor cancer/stromal cell cooperation
por: Melchionna, Roberta, et al.
Publicado: (2020)

Mena regulates nesprin-2 to control actin–nuclear lamina associations, trans-nuclear membrane signalling and gene expression
por: Li Mow Chee, Frederic, et al.
Publicado: (2023)

Women, culture and the HIV epidemic in MENA
por: Chahil-Graf, Renu, et al.
Publicado: (2014)

The Spectrum of Mutations of Homocystinuria in the MENA Region
por: Al-Sadeq, Duaa W., et al.
Publicado: (2020)

Isolation of concanavalin a caps during various stages of formation and their association with actin and myosin
por: Condeelis, J
Publicado: (1979)

EGF-induced PIP(2) hydrolysis releases and activates cofilin locally in carcinoma cells
por: van Rheenen, Jacco, et al.
Publicado: (2007)

Do we need regional guidelines for breast cancer management in the MENA region? MENA Breast Cancer Guidelines project
por: Fayed, Reham, et al.
Publicado: (2017)

HIV surveillance in MENA: recent developments and results
por: Bozicevic, Ivana, et al.
Publicado: (2013)

Introducing and Expanding Newborn Screening in the MENA Region
por: Skrinska, Victor, et al.
Publicado: (2020)

Stroke services in MENA: What is there and what is needed
por: Aref, Hany, et al.
Publicado: (2023)

Mena/VASP and αII-Spectrin complexes regulate cytoplasmic actin networks in cardiomyocytes and protect from conduction abnormalities and dilated cardiomyopathy
por: Benz, Peter M, et al.
Publicado: (2013)

Combining TMEM Doorway Score and Mena(Calc) Score Improves the Prediction of Distant Recurrence Risk in HR+/HER2− Breast Cancer Patients
por: Ye, Xianjun, et al.
Publicado: (2022)

Influenza vaccination situation in Middle-East and North Africa countries: Report of the 7th MENA Influenza Stakeholders Network (MENA-ISN)
por: Al Awaidi, Salah, et al.
Publicado: (2018)

Ena/VASP is required for endothelial barrier function in vivo
por: Furman, Craig, et al.
Publicado: (2007)

Vanadium Compounds as PTP Inhibitors
por: Irving, Elsa, et al.
Publicado: (2017)

Electricity-sector reforms in the mena region: evaluation and prospects
por: Benali, Leila
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_bc4auqlv56g4qo9r9fgpijh7lu