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Loss- and Gain-of-Function Approaches Indicate a Dual Role Exerted by Regulatory T Cells in Pulmonary Paracoccidioidomycosis

Paracoccidioidomycosis (PCM), is a pulmonary fungal disease whose severity depends on the adequate development of T cell immunity. Although regulatory T (Treg) cells were shown to control immunity against PCM, deleterious or protective effects were described in different experimental settings. To cl...

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Detalles Bibliográficos
Autores principales: Bazan, Silvia B., Costa, Tania A., de Araújo, Eliseu Frank, Feriotti, Claudia, Loures, Flávio V., Pretel, Fernando D., Calich, Vera L. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626087/
https://www.ncbi.nlm.nih.gov/pubmed/26512987
http://dx.doi.org/10.1371/journal.pntd.0004189