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In Vitro Mutational Analysis of the β(2) Adrenergic Receptor, an In Vivo Surrogate Odorant Receptor

Many G-protein coupled receptors (GPCRs), such as odorant receptors (ORs), cannot be characterized in heterologous cells because of their difficulty in trafficking to the plasma membrane. In contrast, a surrogate OR, the GPCR mouse β2-adrenergic-receptor (mβ2AR), robustly traffics to the plasma memb...

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Detalles Bibliográficos
Autores principales: Jamet, Sophie, Bubnell, Jaclyn, Pfister, Patrick, Tomoiaga, Delia, Rogers, Matthew E., Feinstein, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626089/
https://www.ncbi.nlm.nih.gov/pubmed/26513247
http://dx.doi.org/10.1371/journal.pone.0141696