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Inhibition on Proteasome β1 Subunit Might Contribute to the Anti-Cancer Effects of Fangchinoline in Human Prostate Cancer Cells

Fangchinoline is a bisbenzylisoquinoline alkaloid isolated from Radix Stephaniae tetrandrae S. Moore. Fangchinoline and its structure analogue, tetrandrine, exhibited direct binding affinity with recombinant human proteasome β1 subunit and also inhibited its activity in vitro. In cultured prostate P...

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Detalles Bibliográficos
Autores principales: Li, Dong, Lu, Yu, Sun, Peng, Feng, Li-Xing, Liu, Miao, Hu, Li-Hong, Wu, Wan-Ying, Jiang, Bao-Hong, Yang, Min, Qu, Xiao-Bo, Guo, De-An, Liu, Xuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626104/
https://www.ncbi.nlm.nih.gov/pubmed/26512898
http://dx.doi.org/10.1371/journal.pone.0141681