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Mucin 1 gene silencing inhibits the growth of SMMC-7721 human hepatoma cells through Bax-mediated mitochondrial and caspase-8-mediated death receptor apoptotic pathways

Mucin 1 (MUC1) is an oncogene that has a crucial role in the pathogenesis and progression of the majority of epithelial malignant tumors. Our previous study demonstrated that MUC1 gene silencing inhibited the growth of SMMC-7721 cells in vitro and in vivo, however, whether this growth inhibition is...

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Detalles Bibliográficos
Autores principales: YUAN, HONGYAN, WANG, JUAN, WANG, FENGLI, ZHANG, NANNAN, LI, QIONGSHU, XIE, FEI, CHEN, TANXIU, ZHAI, RUIPING, WANG, FANG, GUO, YINGYING, NI, WEIHUA, TAI, GUIXIANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626135/
https://www.ncbi.nlm.nih.gov/pubmed/26398332
http://dx.doi.org/10.3892/mmr.2015.4323