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Repeated intra-nigrostriatal injection of phorbol myristate acetate induces microglial senescence in adult rats
Phorbol myristate acetate (PMA), as a potent tumor promoter, may induce microglial senescence. The present study investigated the effect of PMA infection on microglial senescence. From 58 male Sprague-Dawley rats, 10 were randomly selected and divided into a PMA injection group, containing five rats...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626136/ https://www.ncbi.nlm.nih.gov/pubmed/26459397 http://dx.doi.org/10.3892/mmr.2015.4412 |