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Repeated intra-nigrostriatal injection of phorbol myristate acetate induces microglial senescence in adult rats

Phorbol myristate acetate (PMA), as a potent tumor promoter, may induce microglial senescence. The present study investigated the effect of PMA infection on microglial senescence. From 58 male Sprague-Dawley rats, 10 were randomly selected and divided into a PMA injection group, containing five rats...

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Detalles Bibliográficos
Autores principales: LIU, LIN, LUO, XIAO-GUANG, YU, HONG-MEI, FENG, YU, REN, YAN, YIN, YA-FU, SHANG, HONG, HE, ZHI-YI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626136/
https://www.ncbi.nlm.nih.gov/pubmed/26459397
http://dx.doi.org/10.3892/mmr.2015.4412