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Evaluation of a combinatorial RNAi lentivirus vector targeting foot-and-mouth disease virus in vitro and in vivo

Foot-and-mouth disease virus (FMDV) causes a highly contagious disease of cloven-hoofed animals, which leads to serious economical losses. FMDV is not adequately controlled by vaccination or biosecurity measures. To generate genetically modified FMDV-resistant animals, a combinatorial expression cas...

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Detalles Bibliográficos
Autores principales: ZHANG, XIAOXI, ZHENG, HAIXUE, XU, MINJUN, ZHOU, YU, LI, XIANGPING, YANG, FAN, LIU, QINGYOU, SHI, DESHUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626173/
https://www.ncbi.nlm.nih.gov/pubmed/26323462
http://dx.doi.org/10.3892/mmr.2015.4246