Esculentin-2CHa-Related Peptides Modulate Islet Cell Function and Improve Glucose Tolerance in Mice with Diet-Induced Obesity and Insulin Resistance

The frog skin host-defense peptide esculentin-2CHa (GFSSIFRGVA(10)KFASKGLGK D(20)LAKLGVDLVA(30)CKISKQC) displays antimicrobial, antitumor, and immunomodulatory properties. This study investigated the antidiabetic actions of the peptide and selected analogues. Esculentin-2CHa stimulated insulin secre...

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Detalles Bibliográficos
Autores principales: Ojo, Opeolu O., Srinivasan, Dinesh K., Owolabi, Bosede O., Vasu, Srividya, Conlon, J. Michael, Flatt, Peter R., Abdel-Wahab, Yasser H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626215/
https://www.ncbi.nlm.nih.gov/pubmed/26512980
http://dx.doi.org/10.1371/journal.pone.0141549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626215/
https://www.ncbi.nlm.nih.gov/pubmed/26512980
http://dx.doi.org/10.1371/journal.pone.0141549

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