Predose and Postdose Blood Gene Expression Profiles Identify the Individuals Susceptible to Acetaminophen-Induced Liver Injury in Rats

The extent of drug-induced liver injury (DILI) can vary greatly between different individuals. Thus, it is crucial to identify susceptible population to DILI. The aim of this study was to determine whether transcriptomics analysis of predose and postdose rat blood would allow prediction of susceptib...

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Detalles Bibliográficos
Autores principales: Lu, Xiaoyan, Hu, Bin, Zheng, Jie, Ji, Cai, Fan, Xiaohui, Gao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626237/
https://www.ncbi.nlm.nih.gov/pubmed/26512990
http://dx.doi.org/10.1371/journal.pone.0141750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626237/
https://www.ncbi.nlm.nih.gov/pubmed/26512990
http://dx.doi.org/10.1371/journal.pone.0141750

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