The mitochondria-targeted anti-oxidant MitoQ decreases ischemia-reperfusion injury in a murine syngeneic heart transplant model

BACKGROUND: Free radical production and mitochondrial dysfunction during cardiac graft reperfusion is a major factor in post-transplant ischemia-reperfusion (IR) injury, an important underlying cause of primary graft dysfunction. We therefore assessed the efficacy of the mitochondria-targeted anti-o...

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Detalles Bibliográficos
Autores principales: Dare, Anna J., Logan, Angela, Prime, Tracy A., Rogatti, Sebastian, Goddard, Martin, Bolton, Eleanor M., Bradley, J. Andrew, Pettigrew, Gavin J., Murphy, Michael P., Saeb-Parsy, Kourosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Original Pre-Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626443/
https://www.ncbi.nlm.nih.gov/pubmed/26140808
http://dx.doi.org/10.1016/j.healun.2015.05.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626443/
https://www.ncbi.nlm.nih.gov/pubmed/26140808
http://dx.doi.org/10.1016/j.healun.2015.05.007

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