Cargando…

The mitochondria-targeted anti-oxidant MitoQ decreases ischemia-reperfusion injury in a murine syngeneic heart transplant model

BACKGROUND: Free radical production and mitochondrial dysfunction during cardiac graft reperfusion is a major factor in post-transplant ischemia-reperfusion (IR) injury, an important underlying cause of primary graft dysfunction. We therefore assessed the efficacy of the mitochondria-targeted anti-o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dare, Anna J., Logan, Angela, Prime, Tracy A., Rogatti, Sebastian, Goddard, Martin, Bolton, Eleanor M., Bradley, J. Andrew, Pettigrew, Gavin J., Murphy, Michael P., Saeb-Parsy, Kourosh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Original Pre-Clinical Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626443/ https://www.ncbi.nlm.nih.gov/pubmed/26140808 http://dx.doi.org/10.1016/j.healun.2015.05.007

Ejemplares similares

Protection against renal ischemia–reperfusion injury in vivo by the mitochondria targeted antioxidant MitoQ
por: Dare, Anna J., et al.
Publicado: (2015)

Assessment of H(2)S in vivo using the newly developed mitochondria-targeted mass spectrometry probe MitoA
por: Arndt, Sabine, et al.
Publicado: (2017)

Mitochondria-targeted antioxidant therapy with MitoQ ameliorates aortic stiffening in old mice
por: Gioscia-Ryan, Rachel A., et al.
Publicado: (2018)

The mitochondria-targeted antioxidant MitoQ, attenuates exercise-induced mitochondrial DNA damage
por: Williamson, Josh, et al.
Publicado: (2020)

MitoQ Is Able to Modulate Apoptosis and Inflammation
por: Piscianz, Elisa, et al.
Publicado: (2021)

Anthracycline-Induced Vascular Dysfunction: Is MitoQ the Answer?
por: Sawyer, Douglas B.
Publicado: (2020)

Prevention of diabetic nephropathy in Ins2(+/−AkitaJ) mice by the mitochondria-targeted therapy MitoQ
por: Chacko, Balu K., et al.
Publicado: (2010)

Mitochondria-Targeted Antioxidants MitoQ and MitoTEMPO Do Not Influence BRAF-Driven Malignant Melanoma and KRAS-Driven Lung Cancer Progression in Mice
por: Le Gal, Kristell, et al.
Publicado: (2021)

Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ(10), and angiotensin receptor blocker, losartan, on cardiovascular function
por: McLachlan, Jennifer, et al.
Publicado: (2014)

The mitochondria-targeted antioxidant MitoQ attenuated PM(2.5)-induced vascular fibrosis via regulating mitophagy
por: Ning, Ruihong, et al.
Publicado: (2021)

MitoQ Loaded Chitosan-Hyaluronan Composite Membranes for Wound Healing
por: Tamer, Tamer M., et al.
Publicado: (2018)

Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines
por: Dashdorj, Amarjargal, et al.
Publicado: (2013)

The mitochondria‐targeted anti‐oxidant MitoQ protects against intervertebral disc degeneration by ameliorating mitochondrial dysfunction and redox imbalance
por: Kang, Liang, et al.
Publicado: (2020)

Mitochondria-targeted therapeutics, MitoQ and BGP-15, reverse aging-associated meiotic spindle defects in mouse and human oocytes
por: Al-Zubaidi, Usama, et al.
Publicado: (2020)

The Mitochondria-Targeting Agent MitoQ Improves Muscle Atrophy, Weakness and Oxidative Metabolism in C26 Tumor-Bearing Mice
por: Pin, Fabrizio, et al.
Publicado: (2022)

The Effect of MitoQ on Aging-Related Biomarkers: A Systematic Review and Meta-Analysis
por: Braakhuis, Andrea J., et al.
Publicado: (2018)

MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overload
por: Ribeiro Junior, Rogério Faustino, et al.
Publicado: (2018)

Mitoquinone (MitoQ) Inhibits Platelet Activation Steps by Reducing ROS Levels
por: Méndez, Diego, et al.
Publicado: (2020)

MitoQ Inhibits Human Breast Cancer Cell Migration, Invasion and Clonogenicity
por: Capeloa, Tania, et al.
Publicado: (2022)

MitoQ Prevents Human Breast Cancer Recurrence and Lung Metastasis in Mice †
por: Capeloa, Tania, et al.
Publicado: (2022)

Therapeutic potential of the mitochondria-targeted antioxidant MitoQ in mitochondrial-ROS induced sensorineural hearing loss caused by Idh2 deficiency
por: Kim, Ye-Ri, et al.
Publicado: (2018)

Mitochondria‐targeted antioxidant MitoQ reduced renal damage caused by ischemia‐reperfusion injury in rodent kidneys: Longitudinal observations of T (2)‐weighted imaging and dynamic contrast‐enhanced MRI
por: Liu, Xiaoge, et al.
Publicado: (2017)

A mitochondria-targeted derivative of ascorbate: MitoC
por: Finichiu, Peter G., et al.
Publicado: (2015)

MitoQ Blunts Mitochondrial and Renal Damage during Cold Preservation of Porcine Kidneys
por: Parajuli, Nirmala, et al.
Publicado: (2012)

The targeted anti‐oxidant MitoQ causes mitochondrial swelling and depolarization in kidney tissue
por: Gottwald, Esther M., et al.
Publicado: (2018)

Sex-Specific Effects of Nanoparticle-Encapsulated MitoQ (nMitoQ) Delivery to the Placenta in a Rat Model of Fetal Hypoxia
por: Ganguly, Esha, et al.
Publicado: (2019)

The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1
por: Xiao, Li, et al.
Publicado: (2016)

Exposing Mouse Oocytes to MitoQ During In Vitro Maturation Improves Maturation and Developmental Competence
por: Hosseinzadeh Shirzeyli, Maryam, et al.
Publicado: (2020)

Does Antioxidant Mitoquinone (MitoQ) Ameliorate Oxidative Stress in Frozen–Thawed Rooster Sperm?
por: Sun, Lingwei, et al.
Publicado: (2022)

Inhibition of Mitochondrial Redox Signaling with MitoQ Prevents Metastasis of Human Pancreatic Cancer in Mice
por: Capeloa, Tania, et al.
Publicado: (2022)

MitoQ Protects Ovarian Organoids against Oxidative Stress during Oogenesis and Folliculogenesis In Vitro
por: Wang, Jiapeng, et al.
Publicado: (2023)

The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients
por: Escribano-Lopez, Irene, et al.
Publicado: (2016)

Treating Neurodegenerative Disease with Antioxidants: Efficacy of the Bioactive Phenol Resveratrol and Mitochondrial-Targeted MitoQ and SkQ
por: Shinn, Lindsey J., et al.
Publicado: (2021)

MitoNeoD: A Mitochondria-Targeted Superoxide Probe
por: Shchepinova, Maria M., et al.
Publicado: (2017)

MitoQ Modulates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction via Regulating Nrf2 Signaling
por: Zhang, Shengfeng, et al.
Publicado: (2020)

Mitochondrial-Targeted Antioxidant MitoQ-Mediated Autophagy: A Novel Strategy for Precise Radiation Protection
por: Bao, Xingting, et al.
Publicado: (2023)

Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury
por: Martin, Jack L., et al.
Publicado: (2018)

Diversity of the CD4 T Cell Alloresponse: The Short and the Long of It
por: Ali, Jason M., et al.
Publicado: (2016)

The Antioxidant Moiety of MitoQ Imparts Minimal Metabolic Effects in Adipose Tissue of High Fat Fed Mice
por: Bond, Simon T., et al.
Publicado: (2019)

Response to: The mitochondria-targeted antioxidant MitoQ attenuates exercise-induced mitochondrial DNA damage (Williamson et al., available online 6 August 2020, 101,673)
por: Burtscher, Johannes, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_sdk97rk34r9e1ahgbdkud79neo