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Characterization of Protein–Protein Interfaces through a Protein Contact Network Approach

Anthrax toxin comprises three different proteins, jointly acting to exert toxic activity: a non-toxic protective agent (PA), toxic edema factor (EF), and lethal factor (LF). Binding of PA to anthrax receptors promotes oligomerization of PA, binding of EF and LF, and then endocytosis of the complex....

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Detalles Bibliográficos
Autores principales: Di Paola, Luisa, Platania, Chiara Bianca Maria, Oliva, Gabriele, Setola, Roberto, Pascucci, Federica, Giuliani, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626657/
https://www.ncbi.nlm.nih.gov/pubmed/26579512
http://dx.doi.org/10.3389/fbioe.2015.00170