Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells

The discovery of new bioactive compounds from marine natural sources is very important in pharmacological research. Here we developed a Wnt responsive luciferase reporter assay to screen small molecule inhibitors of cancer associated constitutive Wnt signaling pathway. We identified that gliotoxin (...

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Detalles Bibliográficos
Autores principales: Chen, Junxiong, Wang, Chenliang, Lan, Wenjian, Huang, Chunying, Lin, Mengmeng, Wang, Zhongyang, Liang, Wanling, Iwamoto, Aikichi, Yang, Xiangling, Liu, Huanliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626688/
https://www.ncbi.nlm.nih.gov/pubmed/26445050
http://dx.doi.org/10.3390/md13106259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626688/
https://www.ncbi.nlm.nih.gov/pubmed/26445050
http://dx.doi.org/10.3390/md13106259

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