Macrolactone Nuiapolide, Isolated from a Hawaiian Marine Cyanobacterium, Exhibits Anti-Chemotactic Activity

A new bioactive macrolactone, nuiapolide (1) was identified from a marine cyanobacterium collected off the coast of Niihau, near Lehua Rock. The natural product exhibits anti-chemotactic activity at concentrations as low as 1.3 μM against Jurkat cells, cancerous T lymphocytes, and induces a G2/M pha...

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Detalles Bibliográficos
Autores principales: Mori, Shogo, Williams, Howard, Cagle, Davey, Karanovich, Kristopher, Horgen, F. David, Smith, Roger, Watanabe, Coran M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626689/
https://www.ncbi.nlm.nih.gov/pubmed/26473885
http://dx.doi.org/10.3390/md13106274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626689/
https://www.ncbi.nlm.nih.gov/pubmed/26473885
http://dx.doi.org/10.3390/md13106274

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