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Using S. cerevisiae as a Model System to Investigate V. cholerae VopX-Host Cell Protein Interactions and Phenotypes

Most pathogenic, non-O1/non-O139 serogroup Vibrio cholerae strains cause diarrheal disease in the absence of cholera toxin. Instead, many use Type 3 Secretion System (T3SS) mediated mechanisms to disrupt host cell homeostasis. We identified a T3SS effector protein, VopX, which is translocated into m...

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Detalles Bibliográficos
Autores principales: Seward, Christopher H., Manzella, Alexander, Alam, Ashfaqul, Butler, J. Scott, Dziejman, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626723/
https://www.ncbi.nlm.nih.gov/pubmed/26473925
http://dx.doi.org/10.3390/toxins7104099