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Bioactive Mimetics of Conotoxins and other Venom Peptides

Ziconotide (Prialt(®)), a synthetic version of the peptide ω-conotoxin MVIIA found in the venom of a fish-hunting marine cone snail Conus magnus, is one of very few drugs effective in the treatment of intractable chronic pain. However, its intrathecal mode of delivery and narrow therapeutic window c...

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Detalles Bibliográficos
Autores principales: Duggan, Peter J., Tuck, Kellie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626728/
https://www.ncbi.nlm.nih.gov/pubmed/26501323
http://dx.doi.org/10.3390/toxins7104175