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Bioactive Mimetics of Conotoxins and other Venom Peptides
Ziconotide (Prialt(®)), a synthetic version of the peptide ω-conotoxin MVIIA found in the venom of a fish-hunting marine cone snail Conus magnus, is one of very few drugs effective in the treatment of intractable chronic pain. However, its intrathecal mode of delivery and narrow therapeutic window c...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626728/ https://www.ncbi.nlm.nih.gov/pubmed/26501323 http://dx.doi.org/10.3390/toxins7104175 |