Phosphorylation of NR2B NMDA subunits by protein kinase C in arcuate nucleus contributes to inflammatory pain in rats

The arcuate nucleus (ARC) of the hypothalamus plays a key role in pain processing. Although it is well known that inhibition of NMDA receptor (NMDAR) in ARC attenuates hyperalgesia induced by peripheral inflammation, the underlying mechanism of NMDAR activation in ARC remains unclear. Protein kinase...

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Detalles Bibliográficos
Autores principales: Bu, Fan, Tian, Huiyu, Gong, Shan, Zhu, Qi, Xu, Guang-Yin, Tao, Jin, Jiang, Xinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626761/
https://www.ncbi.nlm.nih.gov/pubmed/26515544
http://dx.doi.org/10.1038/srep15945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626761/
https://www.ncbi.nlm.nih.gov/pubmed/26515544
http://dx.doi.org/10.1038/srep15945

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