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Crosslinked chitosan-dextran sulfate nanoparticle for improved topical ocular drug delivery

PURPOSE: To examine the benefits of chitosan-dextran sulfate nanoparticles (CDNs) as a topical ocular delivery system with lutein as a model drug. METHODS: CDNs were developed by polyelectrolyte complexation of positively charged chitosan (CS) and negatively charged dextran sulfate (DS). 1-Ethyl-3-(...

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Detalles Bibliográficos
Autores principales: Chaiyasan, Wanachat, Srinivas, Sangly P., Tiyaboonchai, Waree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626781/
https://www.ncbi.nlm.nih.gov/pubmed/26604662