Cargando…
Retroactive modulation of spike timing-dependent plasticity by dopamine
Most reinforcement learning models assume that the reward signal arrives after the activity that led to the reward, placing constraints on the possible underlying cellular mechanisms. Here we show that dopamine, a positive reinforcement signal, can retroactively convert hippocampal timing-dependent...
Autores principales: | Brzosko, Zuzanna, Schultz, Wolfram, Paulsen, Ole |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626806/ https://www.ncbi.nlm.nih.gov/pubmed/26516682 http://dx.doi.org/10.7554/eLife.09685 |
Ejemplares similares
-
Sequential neuromodulation of Hebbian plasticity offers mechanism for effective reward-based navigation
por: Brzosko, Zuzanna, et al.
Publicado: (2017) -
Postsynaptic burst reactivation of hippocampal neurons enables associative plasticity of temporally discontiguous inputs
por: Fuchsberger, Tanja, et al.
Publicado: (2022) -
Acetylcholine-modulated plasticity in reward-driven navigation: a computational study
por: Zannone, Sara, et al.
Publicado: (2018) -
Temporal Modulation of Spike-Timing-Dependent Plasticity
por: Froemke, Robert C., et al.
Publicado: (2010) -
Dopamine Receptor Activation Is Required for GABAergic Spike Timing-Dependent Plasticity in Response to Complex Spike Pairing in the Ventral Tegmental Area
por: Langlois, Ludovic D., et al.
Publicado: (2018)