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The evolution of tumor metastasis during clonal expansion with alterations in metastasis driver genes

Metastasis is a leading cause of cancer-related deaths. Carcinoma generally initiates at a specific organ as a primary tumor, but eventually metastasizes and forms tumor sites in other organs. In this report, we developed a mathematical model of cancer progression with alterations in metastasis-rela...

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Detalles Bibliográficos
Autores principales: Yamamoto, Kimiyo N., Nakamura, Akira, Haeno, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626809/
https://www.ncbi.nlm.nih.gov/pubmed/26515895
http://dx.doi.org/10.1038/srep15886