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Dendritic Cell Autophagy Contributes to Herpes Simplex Virus-Driven Stromal Keratitis and Immunopathology

Herpetic stromal keratitis (HSK) is a blinding ocular disease that is initiated by HSV-1 and characterized by chronic inflammation in the cornea. Although HSK immunopathology of the cornea is well documented in animal models, events preceding this abnormal inflammatory cascade are poorly understood....

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Detalles Bibliográficos
Autores principales: Jiang, Yike, Yin, Xiaotang, Stuart, Patrick M., Leib, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626854/
https://www.ncbi.nlm.nih.gov/pubmed/26507231
http://dx.doi.org/10.1128/mBio.01426-15