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Evidence for microRNA-31 dependent Bim-Bax interaction preceding mitochondrial Bax translocation during radiation-induced apoptosis

Downregulation of microRNA-31 has been linked with enhanced stress resistance, while its overexpression leads to cell death. In this study, we found mediatory role of microRNA-31 in γ-radiation-induced apoptosis in a model insect cell line Sf9 carrying well-conserved apoptotic machinery. Mature micr...

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Detalles Bibliográficos
Autores principales: Kumar, Ashish, Ghosh, Soma, Chandna, Sudhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626866/
https://www.ncbi.nlm.nih.gov/pubmed/26514984
http://dx.doi.org/10.1038/srep15923