LynA regulates an inflammation-sensitive signaling checkpoint in macrophages

Clustering of receptors associated with immunoreceptor tyrosine-based activation motifs (ITAMs) initiates the macrophage antimicrobial response. ITAM receptors engage Src-family tyrosine kinases (SFKs) to initiate phagocytosis and macrophage activation. Macrophages also encounter nonpathogenic molec...

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Detalles Bibliográficos
Autores principales: Freedman, Tanya S, Tan, Ying X, Skrzypczynska, Katarzyna M, Manz, Boryana N, Sjaastad, Frances V, Goodridge, Helen S, Lowell, Clifford A, Weiss, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626889/
https://www.ncbi.nlm.nih.gov/pubmed/26517880
http://dx.doi.org/10.7554/eLife.09183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626889/
https://www.ncbi.nlm.nih.gov/pubmed/26517880
http://dx.doi.org/10.7554/eLife.09183

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