Hepatic and Nephric NRF2 Pathway Up-Regulation, an Early Antioxidant Response, in Acute Arsenic-Exposed Mice

Inorganic arsenic (iAs), a proven human carcinogen, damages biological systems through multiple mechanisms, one of them being reactive oxygen species (ROS) production. NRF2 is a redox-sensitive transcription factor that positively regulates the genes of encoding antioxidant and detoxification enzyme...

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Detalles Bibliográficos
Autores principales: Li, Jinlong, Duan, Xiaoxu, Dong, Dandan, Zhang, Yang, Li, Wei, Zhao, Lu, Nie, Huifang, Sun, Guifan, Li, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626990/
https://www.ncbi.nlm.nih.gov/pubmed/26473898
http://dx.doi.org/10.3390/ijerph121012628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626990/
https://www.ncbi.nlm.nih.gov/pubmed/26473898
http://dx.doi.org/10.3390/ijerph121012628

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