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Hepatic and Nephric NRF2 Pathway Up-Regulation, an Early Antioxidant Response, in Acute Arsenic-Exposed Mice
Inorganic arsenic (iAs), a proven human carcinogen, damages biological systems through multiple mechanisms, one of them being reactive oxygen species (ROS) production. NRF2 is a redox-sensitive transcription factor that positively regulates the genes of encoding antioxidant and detoxification enzyme...
Autores principales: | Li, Jinlong, Duan, Xiaoxu, Dong, Dandan, Zhang, Yang, Li, Wei, Zhao, Lu, Nie, Huifang, Sun, Guifan, Li, Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626990/ https://www.ncbi.nlm.nih.gov/pubmed/26473898 http://dx.doi.org/10.3390/ijerph121012628 |
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