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Mediator independently orchestrates multiple steps of preinitiation complex assembly in vivo

Mediator is a large multiprotein complex conserved in all eukaryotes, which has a crucial coregulator function in transcription by RNA polymerase II (Pol II). However, the molecular mechanisms of its action in vivo remain to be understood. Med17 is an essential and central component of the Mediator...

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Detalles Bibliográficos
Autores principales: Eyboulet, Fanny, Wydau-Dematteis, Sandra, Eychenne, Thomas, Alibert, Olivier, Neil, Helen, Boschiero, Claire, Nevers, Marie-Claire, Volland, Hervé, Cornu, David, Redeker, Virginie, Werner, Michel, Soutourina, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627066/
https://www.ncbi.nlm.nih.gov/pubmed/26240385
http://dx.doi.org/10.1093/nar/gkv782