A bacterial regulatory RNA attenuates virulence, spread and human host cell phagocytosis

Staphylococcus aureus pathogenesis is directed by regulatory proteins and RNAs. We report the case of an RNA attenuating virulence and host uptake, possibly to sustain commensalism. A S. aureus sRNA, SprC (srn_3610), reduced virulence and bacterial loads in a mouse infection model. S. aureus deleted...

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Detalles Bibliográficos
Autores principales: Le Pabic, Hélène, Germain-Amiot, Noëlla, Bordeau, Valérie, Felden, Brice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627067/
https://www.ncbi.nlm.nih.gov/pubmed/26240382
http://dx.doi.org/10.1093/nar/gkv783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627067/
https://www.ncbi.nlm.nih.gov/pubmed/26240382
http://dx.doi.org/10.1093/nar/gkv783

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