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Cooperation meets competition in microRNA-mediated DMPK transcript regulation

The fundamental role of microRNAs (miRNAs) in the regulation of gene expression has been well-established, but many miRNA-driven regulatory mechanisms remain elusive. In the present study, we demonstrate that miRNAs regulate the expression of DMPK, the gene mutated in myotonic dystrophy type 1 (DM1)...

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Detalles Bibliográficos
Autores principales: Koscianska, Edyta, Witkos, Tomasz M., Kozlowska, Emilia, Wojciechowska, Marzena, Krzyzosiak, Wlodzimierz J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627076/
https://www.ncbi.nlm.nih.gov/pubmed/26304544
http://dx.doi.org/10.1093/nar/gkv849