Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA

Thymine DNA Glycosylase (TDG) performs essential functions in maintaining genetic integrity and epigenetic regulation. Initiating base excision repair, TDG removes thymine from mutagenic G·T mispairs caused by 5-methylcytosine (mC) deamination and other lesions including uracil (U) and 5-hydroxymeth...

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Detalles Bibliográficos
Autores principales: Malik, Shuja S., Coey, Christopher T., Varney, Kristen M., Pozharski, Edwin, Drohat, Alexander C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627079/
https://www.ncbi.nlm.nih.gov/pubmed/26358812
http://dx.doi.org/10.1093/nar/gkv890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627079/
https://www.ncbi.nlm.nih.gov/pubmed/26358812
http://dx.doi.org/10.1093/nar/gkv890

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