Beyond the one-locus-one-miRNA paradigm: microRNA isoforms enable deeper insights into breast cancer heterogeneity

Here we describe our study of miRNA isoforms (isomiRs) in breast cancer (BRCA) and normal breast data sets from the Cancer Genome Atlas (TCGA) repository. We report that the full isomiR profiles, from both known and novel human-specific miRNA loci, are particularly rich in information and can distin...

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Detalles Bibliográficos
Autores principales: Telonis, Aristeidis G., Loher, Phillipe, Jing, Yi, Londin, Eric, Rigoutsos, Isidore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627084/
https://www.ncbi.nlm.nih.gov/pubmed/26400174
http://dx.doi.org/10.1093/nar/gkv922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627084/
https://www.ncbi.nlm.nih.gov/pubmed/26400174
http://dx.doi.org/10.1093/nar/gkv922

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