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Beyond the one-locus-one-miRNA paradigm: microRNA isoforms enable deeper insights into breast cancer heterogeneity
Here we describe our study of miRNA isoforms (isomiRs) in breast cancer (BRCA) and normal breast data sets from the Cancer Genome Atlas (TCGA) repository. We report that the full isomiR profiles, from both known and novel human-specific miRNA loci, are particularly rich in information and can distin...
Autores principales: | Telonis, Aristeidis G., Loher, Phillipe, Jing, Yi, Londin, Eric, Rigoutsos, Isidore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627084/ https://www.ncbi.nlm.nih.gov/pubmed/26400174 http://dx.doi.org/10.1093/nar/gkv922 |
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