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Searching target sites on DNA by proteins: Role of DNA dynamics under confinement
DNA-binding proteins (DBPs) rapidly search and specifically bind to their target sites on genomic DNA in order to trigger many cellular regulatory processes. It has been suggested that the facilitation of search dynamics is achieved by combining 3D diffusion with one-dimensional sliding and hopping...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627088/ https://www.ncbi.nlm.nih.gov/pubmed/26400158 http://dx.doi.org/10.1093/nar/gkv931 |